Low Dose Naltrexone (LDN) has gained attention for its potential in managing various conditions, including autoimmune disorders like rheumatoid arthritis, Crohn’s disease, ulcerative colitis, and also chronic pain.
Naltrexone for Pain & Autoimmune
Many doctors prescribe their patients naltrexone for pain management, especially those seeking alternatives to addictive opioids. Research suggests that LDN may help reduce chronic pain by interacting with the body’s immune response and reducing inflammation, which makes it an attractive option for conditions like fibromyalgia, arthritis, and even some forms of neuropathic pain.
A recent study demonstrated how LDN may reduce pain levels in patients by about 30%. When considering autoimmune diseases, 88% of patients with Crohn’s disease using LDN reported symptom improvements. As a result, patient satisfaction was high, with over 60% of users willing to continue LDN as part of their pain or autoimmune condition management.
LDN compounding pharmacy, Health Dimensions Clinical Pharmacy (HDRx), has attracted many patients looking for advanced options, with expert pharmacists formulating LDN into several medication dosage forms depending on what symptom a patient is targeting.
Low Dose Naltrexone (LDN) from HDRx is Compounded into Several Forms
LDN IS PRESCRIBED FOR MORE THAN JUST PAIN & AUTOIMMUNE
Explore LDN’s potential applications across different systems and types of conditions.
- Chronic Pain and Inflammation:
- Chronic Pain
- Arthritis
- Fibromyalgia
- Neuroinflammation
- Inflammation
- Autoimmune and Inflammatory Diseases:
- Hashimoto’s Disease
- Graves’ Disease
- Sjogren’s Syndrome
- Lupus
- Multiple Sclerosis
- Psoriasis
- Eczema
- Celiac Disease
- Metabolic and General Health:
- Weight Loss
- Gastrointestinal Conditions:
- Crohn’s Disease
- Ulcerative Colitis
- Irritable Bowel Syndrome (IBS)
- Neurological and Psychiatric Disorders:
- Parkinson’s Disease
- Alzheimer’s Disease
- Autism
- Traumatic Brain Injury (TBI)
- Immune-Related and Infectious Conditions:
- HIV/AIDS
- Lyme Disease
- Cancer
- Veterinary Applications:
- Animals
RELATED STUDIES & LITERATURE ABOUT LDN
Patten, D. K., Schultz, B. G., & Berlau, D. J. (2018). The safety and efficacy of low‐dose naltrexone in the management of chronic pain and inflammation in multiple sclerosis, fibromyalgia, Crohn’s disease, and other chronic pain disorders. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 38(3), 382–389. [Read Article]
Moore, E. A., & Wilkinson, S. (2008). The promise of low dose naltrexone therapy: potential benefits in cancer, autoimmune, neurological and infectious disorders. McFarland. [Read Book]
Trofimovitch, D., & Baumrucker, S. J. (2019). Pharmacology update: low-dose naltrexone as a possible nonopioid modality for some chronic, nonmalignant pain syndromes. American Journal of Hospice and Palliative Medicine®, 36(10), 907–912. [Read Article]
Kim, P. S., & Fishman, M. A. (2020). Low-dose naltrexone for chronic pain: update and systemic review. Current Pain and Headache Reports, 24(10), 64. [Read Article]
Smith, J. P., Stock, H., Bingaman, S., Mauger, D., Rogosnitzky, M., & Zagon, I. S. (2007). Low-dose naltrexone therapy improves active Crohn’s disease. Official journal of the American College of Gastroenterology| ACG, 102(4), 820–828. [Read Article]
De Carvalho, J. F., & Skare, T. (2023). Low-dose naltrexone in rheumatological diseases. Mediterranean Journal of Rheumatology, 34(1), 1–6. [Read Article]
Li, Z., You, Y., Griffin, N., Feng, J., & Shan, F. (2018). Low-dose naltrexone (LDN): A promising treatment in immune-related diseases and cancer therapy. International immunopharmacology, 61, 178–184. [Read Article]
What to Avoid When Taking Low Dose Naltrexone
While LDN offers many potential benefits, it’s important to be aware of what to avoid when taking low dose naltrexone to help improve safety and patient outcomes.
- Opioids and Narcotics
One of the most critical things to avoid when taking LDN is any medications or substances that contain opioids. Since naltrexone blocks opioid receptors, using both simultaneously may cause withdrawal symptoms and negate pain management. Always consult your healthcare provider before using LDN if you’re taking any opioid-based medications. - Alcohol
While low doses of naltrexone isn’t typically used for alcohol dependence, it’s still recommended to limit alcohol intake while on LDN. Alcohol may interfere with how your body processes the medication, potentially leading to low dose naltrexone side effects such as dizziness, vomiting, or sleep disturbances. - Overuse of Anti-Inflammatory Drugs
LDN works by modulating the immune response and reducing inflammation. Overuse of certain anti-inflammatory medications, particularly non-steroidal anti-inflammatory drugs (NSAIDs), may reduce the clinical response of LDN. If you need anti-inflammatories, consult your doctor or pharmacist to know proper dosing and safety. - Inconsistent Dosing
Consistency is the key to maximizing the potential of LDN. Missing doses or not taking LDN on time can diminish therapeutic effects.
Low Dose Naltrexone Side Effects
While LDN is generally well-tolerated with minimal side effects, it’s essential to be aware of the possible side effects. Some common low dose naltrexone side effects include:
- Vivid dreams or sleep disturbances
- Nausea
- Headaches
- Fatigue or dizziness
These side effects are typically mild and often diminish after a few weeks of use. However, consult your healthcare provider immediately if you experience persistent or severe symptoms. HDRx is here to assist you with managing any side effects by offering patient consultations and personalized dosing plans.
How HDRx May Help
At HDRx, we’re committed to supporting you throughout your LDN journey.
Here’s how we may help:
- Customized Compounded LDN: We offer personalized formulations in the appropriate dosage form, with precision tailored to your exact dosage needs.
- Provider Consultations: Our pharmacists are available to discuss LDN therapy, answering any questions from patients or providers.
- Convenient Prescription Refills and Delivery: Patients fill out our online Prescription Refill Request Form with prescription, or practitioners may easily submit prescriptions using our Rx Order Forms. HDRx is licensed to fill and ship medications to multiple states with valid prescription: MI, OH, IN, IL, IN, WI, and MN.
Maximizing the Potential of Low Dose Naltrexone
Low Dose Naltrexone has shown therapeutic potential for managing pain, autoimmune conditions, and more. The pharmacy you choose for LDN matters. Health Dimensions Clinical Pharmacy (HDRx) is Michigan’s trusted pharmacy for Compounded LDN, consultations, and ongoing care to make sure your therapy is well-suited to patient needs. Serving Farmington Hills, West Bloomfield, Northville, Detroit, and beyond — we’re here to help patients achieve their health improvement goals.
Patients deserve care personalized to their specific needs, and we’re here to make sure that’s just what they receive, every time. Contact us today for more information or to discuss how we can help make your LDN journey the best experience possible.
